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Best MSM (Methylsulfonylmethane) Powder Supplements for 2023


A quick overview of the top scoring MSM powder supplements:


What is Methylsulfonylmethane (MSM)?

Methylsulfonylmethane (MSM) is a naturally occurring chemical found in most living organisms. The benefits of MSM include anti-inflammatory and anti-oxidant properties. Studies have shown that it can reduce the levels of oxidative free radicals in the body. While it has not been studied as a supplement for preventing disease, there are indications that it could be beneficial for a number of medical conditions. These include arthritis, leaky gut syndrome, chronic pain, osteoporosis, and even hay fever. It is also being studied for its hair-growing properties.


Methylsulfonylmethane has also been tested for various medical conditions, including arthritis, leaky gut syndrome, chronic muscle pain, and neuropathy. However, it has not been approved by the FDA as a prevention supplement. There are also no studies on the long-term safety of methylsulfonylmethane. A few side effects have been reported, including allergic reactions, upset stomach, and rashes on the skin.


There are several dietary sources for MSM, including red meat, milk, and certain fruits and vegetables. For example, strawberries, tomatoes, swiss chard, and corn are among the many foods that contain methylsulfonylmethane. Other dietary sources of this compound can be found in coffee and bread. Dietary supplements can also be manufactured from lab-made MSM which may also contain botanicals and amino acids. When you take a dietary supplement, make sure you drink plenty of water. Drinking a lot of water will help to increase the amount of methylsulfonylmethane in your body.


Methylsulfonylmethane can be purchased as a topical cream or a powder supplement. Dosages vary but in humans but methylsulfonylmethane is known to be safe at dosages of between 1.5 and 10 grams daily. The long-term safety of this compound is not well understood and could product side effects such as bloating, indigestion, and stomach upset. If you experience any of these side effects, stop using the supplement immediately and see your health care professional.

What are the benefits of MSM?

MSM is a dietary supplement that is composed of the organic compound methylsulfonylmethane, which is sometimes used to help with conditions such as joint pain, osteoarthritis, and inflammation. Some people also use it to help with skin conditions and allergies. However, it is important to note that there is limited scientific research to support the effectiveness of MSM for these conditions. Some of the potential benefits of MSM include:

  1. Reducing pain and inflammation: Some studies have found that taking MSM supplements may help reduce pain and inflammation in people with conditions such as osteoarthritis.

  2. Improving skin health: Some people use topical MSM to help with conditions such as eczema and psoriasis, but more research is needed to confirm the effectiveness of this use.

  3. Improving hair and nail health: Some people use MSM supplements to improve the strength and appearance of hair and nails, but more research is needed to confirm the effectiveness of this use.

  4. Improving immune system function: Some preliminary research suggests that MSM may help boost the immune system and reduce the risk of certain infections.

It's worth noting that more research is needed to confirm these potential benefits of MSM, and the safety and effectiveness of MSM may vary depending on a person's individual health status and the specific condition being treated. It's always a good idea to consult with a healthcare professional before starting to use any dietary supplement.

What are the risks of taking MSM?

There are currently no known major risks associated with taking MSM supplements in the recommended doses. MSM is considered safe for most adults when taken orally in doses of up to 3 grams per day for up to 12 weeks. However, there is not enough information about the safety of long-term use or of using MSM in higher doses.

Some people may experience minor side effects such as stomach upset, diarrhea, or skin irritation when taking MSM supplements. These side effects are generally mild and go away on their own.

As with any supplement, it is always important to speak with a healthcare provider before taking MSM, especially if you have a medical condition or are taking any medications. Pregnant and breastfeeding women should also avoid taking MSM without consulting with a healthcare provider.

It's also worth noting that MSM supplements are not regulated by the FDA in the same way that medications are, so the quality and purity of the supplements may vary. It's recommended to purchase MSM supplements from reputable manufacturers and distributors.

How much MSM should I take?

The recommended dosage of MSM varies depending on the reason for taking it and the form in which it is taken.

  • For osteoarthritis and rheumatoid arthritis: a dosage of 2-6 grams per day of MSM has been used in clinical studies.

  • For muscle pain: A dosage of 1-2 grams of MSM twice a day has been used in clinical studies.

  • For general health and well-being: A dosage of 500-1000mg of MSM per day is often recommended.

It is important to note that these recommendations are general and may not be appropriate for everyone. It's always best to consult with a healthcare provider before starting any new supplement, especially if you have a medical condition or are taking any medications. It's also worth noting that the effects of MSM may not be noticed immediately, it may take several weeks to see any benefits. Start with a lower dose and increase gradually, if necessary.











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